| 付鸿江,施 悦.血管腔内介入联合负压封闭引流治疗糖尿病足疗效分析[J].中国烧伤创疡杂志,2025,(4):270~273. |
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| 中文关键词: 负压封闭引流 血管腔内介入 糖尿病足 踝肱指数 疼痛 截肢 复发 |
| 英文关键词:Vacuum sealing drainage Endovascular intervention Diabetic foot Ankle⁃brachial index Pain Amputation Recurrence |
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| 中文摘要: |
| 【摘要】 目的 分析血管腔内介入联合负压封闭引流治疗糖尿病足的临床疗效。 方法 选取2021年4月至2023年4月泰达国际心血管病医院收治的80例糖尿病足患者作为研究对象, 按照不同治疗方法将其分为研究组 (40 例) 与对照组 (40 例)。 研究组患者行血管腔内介入+负压封闭引流治疗, 对照组患者在药物改善微循环的基础上行负压封闭引流治疗, 对比两组患者创面疼痛程度、创面愈合能力、踝肱指数、创面愈合率、截肢率及复发率。 结果 治疗 1、2、3 周后, 研究组患者创面疼痛程度明显低于对照组 ( t = 9.545、8.319、9.003, P 均< 0.001); 治疗 2、4、6 周后, 研究组患者创面愈合能力明显优于对照组 ( t = 4.936、5.187、5.487, P 均 < 0.001); 治疗 1、2、3 个月后, 研究组患者踝肱指数明显高于对照组 ( t = 5.451、4.954、4.721, P 均<0.001); 研究组患者创面愈合率明显高于对照组 ( χ 2 = 4.528, P = 0.033)、截肢率明显低于对照组 ( χ 2 = 4.588, P = 0.032); 随访 12 个月, 研究组患者复发率明显低于对照组 ( χ 2 = 11.114, P<0.001)。 结论 血管腔内介入联合负压封闭引流能够通过重建血运以及负压作用提高创面愈合能力, 加快创面再生修复, 减轻创面疼痛, 降低截肢率及复发率。 |
| 英文摘要: |
| 【Abstract】 Objective To analyze the clinical efficacy of endovascular intervention combined with vacuum sealing drainage in the treatment of diabetic foot. Methods 80 patients with diabetic foot admitted to TEDA International Cardio?vascular Hospital from April 2021 to April 2023 were enrolled as research subjects and divided into the study group (n = 40) and the control group (n = 40) according to different treatment methods. Patients in the study group were treated with endovascular intervention combined with vacuum sealing drainage, while those in the control group were treated with vacuum sealing drainage on the basis of drug therapy for microcirculation improvement. Wound pain intensity, wound healing ability, ankle?brachial index, wound healing rate, amputation rate, and recurrence rate were compared between the two groups. Results After 1, 2 and 3 weeks of treatment, wound pain intensity of patients in the study group was significantly lower than the control group ( t = 9.545, 8.319 and 9.003, all P< 0.001). After 2, 4 and 6 weeks of treatment, the woundhealing ability of patients in the study group was significantly better than the control group ( t = 4.936, 5.187 and 5.487, all P<0.001). After 1, 2 and 3 months of treatment, the ankle?brachial index of patients in the study group was significantly higher than the control group (t = 5.451, 4.954 and 4.721, all P<0.001). The wound healing rate in the study group was significantly higher (χ 2 = 4.528, P= 0.033), and the amputation rate was significantly lower than the control group ( χ 2 =
4.588, P= 0.032). During the 12?month follow?up, the recurrence rate in the study group was significantly lower than the control group (χ 2 = 11.114, P<0.001). Conclusion Endovascular intervention combined with vacuum sealing drainage can improve wound healing ability and accelerate wound regeneration and repair by reconstructing blood flow and applying
negative pressure, thereby reducing wound pain, amputation rate, and recurrence rate. |
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