• 湿润烧伤膏联合中药熏洗治疗Ⅰ期肛裂疗效分析
  • Analysis on the Clinical Efficacy of MEBO in Combination with TCM Fumigation in the Treatment of Stage Ⅰ Anal Fissure
  • 张 仑,张 勇,闵振兴,孔祥涛.湿润烧伤膏联合中药熏洗治疗Ⅰ期肛裂疗效分析[J].中国烧伤创疡杂志,2018,(3):221~226.
    DOI:
    中文关键词:  湿润烧伤膏  中药熏洗  Ⅰ期肛裂  硝酸甘油软膏  疗效
    英文关键词:MEBO  TCM fumigation  Stage Ⅰ anal fissure  Nitroglycerin ointment  Clinical efficacy
    基金项目:
    作者单位
    张 仑 北京市宣武中医医院外科 
    张 勇 北京市宣武中医医院外科 
    闵振兴 北京市宣武中医医院外科 
    孔祥涛 北京市宣武中医医院外科 
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    中文摘要:
          【摘要】 目的 探讨湿润烧伤膏联合中药熏洗治疗Ⅰ期肛裂的临床疗效。方法 采用随机数表法将2016年10月—2017年9月北京市宣武中医医院外科收治的75例Ⅰ期肛裂患者随机分为治疗1组(30例)、治疗2组(30例) 与对照组(15例), 其中治疗1组患者采用湿润烧伤膏联合中药熏洗治疗, 治疗2组患者采用湿润烧伤膏治疗, 对照组患者采用硝酸甘油软膏治疗, 对比观察3组患者的创面疼痛程度、便血情况、创面愈合时间及临床疗效。结果 治疗10d后, 3组患者临床疗效两两对比, P均<0.01, 差异具有统计学意义; 3组患者肛裂创面愈合时间两两对比, P均<0.05, 差异具有统计学意义; 治疗第3、7天, 治疗1组与治疗2组肛裂创面VAS疼痛评分及便血评分对比, P均<0.05, 差异具有统计学意义。结论 湿润烧伤膏联合中药熏洗治疗Ⅰ期肛裂,可有效缓解创面疼痛, 减少排便出血量, 促进创面愈合, 缩短创面愈合时间, 疗效显著, 且操作简便, 安全可靠, 值得临床推广应用。
    英文摘要:
          【Abstract】 Objective To study the clinical efficacy of MEBO in combination with TCM fumigation in the treatment of stage Ⅰ anal fissure. Methods Patients with stage Ⅰ anal fissure, admitted to Surgery Department of Beijing Xuanwu TCM Hospital from October 2016 to September 2017 were divided, according to the random number table, into treatment group 1 (30 cases), treatment group 2 (30 cases) and control group (15 cases). Patients in the treatment group 1 were treated with MEBO in combination with TCM fumigation, those in the treatment group 2 with MEBO and those in the control group with nitroglycerin ointment. Pain degree, hematochezia, wound healing time and treatment process were observed and compared among the three groups. Results Clinical efficacy and the healing time of anal fissure wound were compared between any two of the three groups and the results all showed statistically significant difference (all P<0.01);VAS pain score and hematochezia of patients in treatment group 1 and 2 were compared on day 3 and 7 of the treatment and the results both showed statistically significant difference (both P<0.05). Conclusion The therapy of MEBO in combination with TCM fumigation in the treatment of stage Ⅰ anal fissure, apart from its simple and easy operation, application safety and reliability, can effectively alleviate wound pain and bleeding during defecation, promote wound healing and reduce wound healing time, deserving to be promoted in clinical practice.